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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5424051c8aca25636f86d16d963b747b8d6316a5c3328d82ce73e4fe0e599a37' 
  AND token = 'HK7VKKkLbzGbIWuu01ukeolFDaihTKm2u6B5T6ncRyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}