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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f69f7b97d6c9fbcf726bbc014382900ca50a4bdf47a12a71c43e7c0a79149e05' 
  AND token = 'vt8of5FLZ5BpSEAkvseGllz/zEnu7B3xsm69PC7/I40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}