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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0974ddccb8634e9d25376df9ee6fa6b2f491edf08e1c6c51ca52763554054a9f' 
  AND token = 'AxVgOutOzPja6/LPIeoar5yfO2kRwDIcN3SnZAU4f9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}