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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '863dddeb7bbb7ac916f6db34fd34f61ae1316b0ee7ac2ab38434649b55d30363' 
  AND token = 'IU1qWyWXFa1hp79eYxRvGIeEsQuIy+9uhrCkB5MPCXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}