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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3996b01f3ddbdeda182a4f57afe4fcef9fab9c3fa1774c8642c7479586b4bfa4' 
  AND token = '2AJT7LyaXrzx/n4d2xIVQnmT7fax2U1HhcINXuxrsO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}