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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '382ecb57dbb75c6a3783c5221705872413cd11455b9f76d7c70417b059744f9a' 
  AND token = '3Q+51Spm2CeIy4syx0yZKVg5aPLbUMnvQY0vKI8JBe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}