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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d3a0f5ad214415644b96057ee4a3ac00c4775fb013fbaa17e232e4e0b116647' 
  AND token = 'CIBbWezsPo27dG6VSlxMD3J2qQ+c5W6vSaXbeb7y11s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}