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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1e1cc5346d3a6c4849700c9186fa6607ba044748339f23529b3bca0e44e8407' 
  AND token = 'lLnPoJ2F/sMusS6je1yLCuJ0rK2rx5+FrjcnQjA2Zp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}