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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd843781754f8ece18f8c1ecf4031a766e12d3eb5e3d40a20ead143e2be1521e0' 
  AND token = 'e2D05TBsxbzSq5P2/gL7T9PwFsU9gkNxaBfcnfzNuG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}