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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29ac2595ed71a779aa4ff5c3a6e7c65ec57e01c32aaadbd6b76b92609cfe99fa' 
  AND token = 'TkMGejfB3xNz77/aN0t+PQWJnigoCg/uMO1X7ZK8KL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}