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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8804681d888f4a9e0807855819e461ceb50d1eb439dbbf9f5ed7d1d778e7cd4d' 
  AND token = 'S9I5S66DPsPrVesr9G/qyY7DT8jgzo7erAMb6RPjLf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}