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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c9a70ac0422380a489a72ee7489bcafebbbb41b7f71e6498254952af4254ff4' 
  AND token = 'fuwrdY5lY9r8Kl90ixwTl9z8SIWL3Q5gOaZI/JGCExo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}