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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16210a2c8b0de1a1a8f06985b5932eb92fc5c8b8f3d70d0fb75cce42102dff65' 
  AND token = 'oQtYa+DxX+zpFdk2CK5g1z03d4JZkd9WhQYNTxwqgKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}