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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd82411f62d50027bdf7d3030b33e7f59e1dcb759f07f5b1e74b69957997d04f' 
  AND token = 'Qt0ajsqnIB4WZVFf26A5JlnHjD4vSjHTCrDnWZVrVio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}