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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '078ddd6b131337e6e183f3ca770ac2fedf1f52659ce5a551729c2e4d6a2b8747' 
  AND token = 'U7l8U9pynxP9cPsHQwliQ5LiwIbsaWyter1jF8YH0kk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}