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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1016e1e07fd573ba49d1e7e7bbf47cdee1742ae5ede7259666011240f6137c5e' 
  AND token = 'Q/VMnypRr3SgaE8WBg+m2/CXTPoB6waILeTVAr/eepQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}