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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c620c66fc879a7f5ac9af2341f67d81ed301e124d5f1171988b9f8fb6e36f0a8' 
  AND token = 'rxNHqFx7DF6roYFWVXK/atLO0PP1garAuu2sX2dY2Qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}