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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9ed2968c9666601e1b97efc05909d3389d389df8170123c32b0982333a4c0d5' 
  AND token = 'E5lqB75cMk/Zo0NZph6E6ofClw/JaTbiMIL4aiFqJKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}