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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd9d25a9b44444bb95f7d9617b3836dc9f8a91dde28e2aa92ae6200b9e90a788' 
  AND token = 'oVf6N/55U5Uo+l1/4X8OZv7N82V30JQ9bvvBVb0KZLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}