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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0806d4b7bf71e2dc1800213b6e8201cd1347b87c5649f336fd832bad88d10de9' 
  AND token = '9jsv48+2xfO345B86nMvfwB98VpG9oEVwr3QusoHbJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}