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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a5e4fc2691c458bc2ee01d805233c6787496b2702cb7ff38dfc89f8697b02e8' 
  AND token = 'WO6jMd8kE9neuvXKUPr9PZhFeAaCpGybyywyz1lfXnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}