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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34505d922f5fb45dd6400920d58eb79e031d46d45dc60ee1e115e405afd0b11d' 
  AND token = '0L9U6OcmY1l5/ODOM19c1LJ6x1t6O1rmUm+fTTOzRT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}