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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e3213f1b2df013cdf06896dd82b5d092676bc243ad0b8891c751bd1371289af' 
  AND token = 'vkXJxez8AEMz+ccVwg2EX9s3JGuEdtgREYIjfzLX2sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}