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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b49ad9c62a8755c07abf883bd09384f5de3718c04fc02c1cb073fd63f2d9ebc6' 
  AND token = 'ICQ+Ewx6YuabT77Q11skB36RmhAn7RB877U9MA+vte8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}