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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cc385980c9f0b33f6003ddbe3e6b1d1cc48df3b324542585ba392fd94d56b52' 
  AND token = 'qabxdPrMh7gDBOjXFJDAsZLbP3fi3qtXdBuz6kUIVUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}