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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12748167e4713f7bc8040cfde749a710ecb5a6cc5ff04f23db72a8259be6cfa4' 
  AND token = 'mlg0pUeVAdRX+HdGSRFBf91Jl/NeT1Q0YX/5Tww+ljY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}