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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5216ada14828f4579ee68c6e2cb2698c08a9e291ce93a72e1c0486f9ce14ede1' 
  AND token = '9PESqDNYTx7IX/RCt21u96Nv4zbfqtyA8+1FV1hgId0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}