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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64e426e93ec3c43e3a86dc2ef3515a50e6480ca754d9eb34a5d250776e328f48' 
  AND token = 'iwv5ESp5LOEfrxhZFpNHhSdH4TWD5nJWias9hXWXsuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}