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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2f03314b979ef73fc64fe892f0e8ed3fe7f2686879e5976a86a445a7bf58d95' 
  AND token = 'P/BaWlfA9r1tl4YcxpRgR6FBJxFt9YhDUBW2qU2i6sA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}