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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cb6b0aa4fe34d9e20f0fc958d11252065d5107bf2bc2ffa62927352f07198f2' 
  AND token = 'srVVMD1E2XZR/5boewPxLV05ix86eO0O6E1rq77ZFtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}