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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ef07824671b023ba1fd41bdcdbfb5cae5443e12c0a21a0d84b8c052abece77e' 
  AND token = 'd7Yj7Ky+hR1BbTNtf9nGF9bLU68TLJlxwOvWeUDT1wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}