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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44efef0e4e98a888b3ece67ea3d929a9c92b3afd8520818da84b50b1273b139e' 
  AND token = '3id9cgpvTYkR2WJTRfaQN3CninJsb0KPredIfsv7U00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}