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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd281660ba48ad1dd150f9f806bc9dcb4cec2f9cf9d9b4f0150d253f1d4a6c4c1' 
  AND token = '4eIp4rhtz8oaB+9h0s8SjGWElfX4FS5JNXpGHCoxIes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}