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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e88471fc1452007b47b2965a041902501d085b7227a67a79d27e14f83ab456c' 
  AND token = 'n2mAsiSMIHJlR+RA9Y5PPVt7jPC4kiR0wFi9Srfokes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}