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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75a7e11c11a414b5c1857036158ad542f8c14a8a337e190cd6829afad4b20060' 
  AND token = 'TSs5PN/X0+9So7tYobS+FzVOVejKDcCTvNVgyRIrhuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}