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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca871f8a1da0363ea648a4b1f13933b542c25b3d5323acdcb760347f292ba7b0' 
  AND token = 'GZzrX3Kw2YQD8/0V1fbfk13u3JBN6ilX61uWaa3rhxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}