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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c728a9654d95040c8ae0416d03dd75cfc2a02f65cad1ab2086398a4011dc04fe' 
  AND token = 'k5ilpABW9Rj8cDV3srqRY/NcjCyBug8TwFqO1DQtF+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}