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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3d234277cd504f14919a425e26083cd34fe213e6caeddff5ba8c22b956003d6' 
  AND token = '+TxtabwSBVyt0c3l9OCKPAlCmEolIIJwxn6fAP95L2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}