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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ccc8a359185065226f6557d9dd7c682feac7703ef4e1a1ef5ad51f6e8d2a229' 
  AND token = 'LgVeshggWW4Ll+upwsaJ7Q9vVQa6CkkSg/sB6pFnLio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}