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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c9f4878ef72f933fca918d4289fffec6470472f3f6cc5340d49dadf3241a6e1' 
  AND token = 'sqTyG8CHsPAjXDTGbEfns/1WxWY7GkFQHI2g9aMQL4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}