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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9a87cce48496f229e189fb1393f4dfa27d452cf0705fa5e2f7c4a577e4245e8' 
  AND token = 'sXvvLoqPDap5iXJv1hOizomtKbaEki9ziJaI0+/Y0zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}