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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed60ece18812d5d7480e3de9243711dd8fba6f4538c692e741817fab9c654267' 
  AND token = 'xavAdTmIbsKYPiIgkqVH6Ar/kdeJLWNfXmYta26TW5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}