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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '001a26b4da41e352bce18777267e3c6be4f752b049225d4114c50131910129c1' 
  AND token = 'jefvFL4pgO0VFecuSNKnyL4QRobIMrt5cJAdfC+XTq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}