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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '581ec10b6571c238e56e2fc1c7d975af048dba10793be54fd43a40cee873af95' 
  AND token = 'CQX/qwA/GcGh9I0iT3K30vc6mqYSF8GqoxdsVd98kfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}