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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca8d35a9edc7230c06f3f14da3ba255760186fdc352c9aeec7619b3e50f3f003' 
  AND token = 'hDMz8jgpgatlrRzlCEWtsPgc7TmBQFUyUyIQbc5dVT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}