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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bcbf5f2b7cc0f185d43a6330b77e147f398cc153e9c0e5b10450e63f2ba40f4' 
  AND token = 'HNPxxIUdOzU8N2aXnX0/Rb1XgYtXgDOTNfcwaijcTOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}