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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e051888f7555fc4925d6ce2b2de46d85a34db1fbc299cda753f4a811bddb816' 
  AND token = 'wc9MvX5o/kpxE2T0lvd7zdGZXmPGLIJocg+2K1uFPdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}