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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44e3bed6e39520d10f301badb91c51f8e33c98a0a024c36039252fa46e296f8f' 
  AND token = 'xqIMwalXfiuN30bswkmBeZDY8kM7cg/buVvw3w47rBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}