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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '601fa63554be826b184e66a77b7d42669ae17b74b1005c75813dbeacbbbc4b55' 
  AND token = 'SVMPsq28weg2AnSm/SP4GC3p9NnIuZGru+uNKUM8Lpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}