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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15808327cb3624268c76ff6b26ebf1ca7d2dea07a7e62f5ade0ee28317f714a5' 
  AND token = 'SEDrN+YFHZejArv3iKJa6SxoZgyK+PwrYAaBzC7z0Uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}